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Success model results for the new relation between mammographic occurrence and risk off cancer of the breast demise, stratified by the tumefaction characteristics, AJCC values I–IV mutual*
* Fully adjusted model includes covariates podÅ‚Ä…czenie growlr for AJCC stage (I, IIA, IIB, III, IV), registry (five sites), age at diagnosis (30–44, 45–49, 50–54, 55–59, 60–64, 65–69, 70–74, 75–79, ?80 years), year of diagnosis (1996–1998, 1999–2001, 2002–2003, 2004–2005), body mass index (18.5 – <25, 25 – <30, ?30kg/m 2 ), mode of detection (screen-detected, interval-detected, other screen, clinically detected, other), surgery/radiation (no breast surgery, breast conserving therapy without radiation, breast conserving therapy with radiation, other surgery), chemotherapy (yes/no), and annual median income (<$42 000, $42 000 – <$52 000, $52 000 – <$66 000, ?$66 000). Women with missing covariate information were excluded. AJCC = American Joint Committee on Cancer; BI-RADS = Breast Imaging Reporting and Data System; CI = confidence interval; ER = estrogen receptor; HR = hazard ratio; PR = progesterone receptor.
† P-really worth regarding Wald statistic to test for an overall total effectation of categorical BI-RADS occurrence. Most of the analytical evaluating was indeed two-sided.
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007); specifically, elevated risk associated with having almost entirely fatty breasts was apparent for obese women (BMI ?30kg/m 2 , HR = 2.02, 95% CI = 1.37 to 2.97) but not overweight (BMI 25 – <30kg/m 2 , HR = 0.70, 95% CI = 0.40 to 1.23) or lean (BMI 18.5 – <25kg/m 2 , HR = 1.27, 95% CI = 0.74 to 2.17) women. To determine whether this association was being driven by a subgroup of women who were morbidly obese (BMI ?40kg/m 2 ), we conducted post hoc analyses after excluding 313 morbidly obese women, of whom 47 died of breast cancer. In BMI-stratified results, the elevated risk associated with having almost entirely fatty breasts remained apparent for obese women (BMI 30 – <40kg/m 2 , HR = 1.68, 95% CI = 1.07 to 2.63), and the interaction between breast density and BMI was still statistically significant (P = .01).
We discovered a statistically tall communication between Body mass index and you will BI-RADS occurrence with regards to cancer of the breast passing (P for communication =
* BI-RADS, Nipple Imaging Revealing and you may Research Program; Body mass index, bmi; CI, rely on period; Hour, risk ratio. The tumors: Bmi ? thickness telecommunications, P = .007.
† Fully adjusted model includes covariates for American Joint Committee on Cancer stage (I, IIA, IIB, III, IV), registry (five sites), age at diagnosis (30–44, 45–49, 50–54, 55–59, 60–64, 65–69, 70–74, 75–79, ?80 years), year of diagnosis (1996–1998, 1999–2001, 2002–2003, 2004–2005), mode of detection (screen-detected, interval-detected, other screen, clinically detected, other), surgery/radiation (no breast surgery, breast conserving therapy without radiation, breast conserving therapy with radiation, other surgery), chemotherapy (yes/no), and annual median income (<$42 000, $42 000 – <$52 000, $52 000 – <$66 000, ?$66 000). Women with missing covariate information were excluded.
‡ P worthy of from Wald figure to evaluate to own an overall effect of categorical BI-RADS occurrence. All mathematical evaluating was several-sided.
We discovered a statistically significant interaction anywhere between Bmi and you may BI-RADS thickness when it comes to breast cancer passing (P getting interaction =
* BI-RADS, Breast Imaging Revealing and you may Data Program; Body mass index, body mass index; CI, rely on period; Hour, threat proportion. All of the cancers: Bmi ? thickness interaction, P = .007.
† Fully adjusted model includes covariates for American Joint Committee on Cancer stage (I, IIA, IIB, III, IV), registry (five sites), age at diagnosis (30–44, 45–49, 50–54, 55–59, 60–64, 65–69, 70–74, 75–79, ?80 years), year of diagnosis (1996–1998, 1999–2001, 2002–2003, 2004–2005), mode of detection (screen-detected, interval-detected, other screen, clinically detected, other), surgery/radiation (no breast surgery, breast conserving therapy without radiation, breast conserving therapy with radiation, other surgery), chemotherapy (yes/no), and annual median income (<$42 000, $42 000 – <$52 000, $52 000 – <$66 000, ?$66 000). Women with missing covariate information were excluded.