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21 Jan: «—extract range» and you may «—ban diversity» don’t error away whenever the type in data contain a great chromosome password absent on current https://datingranking.net/de/alleinerziehende-dating/ dataset.
: Fixed —meta-analysis-se-occupation insect. —meta-analysis-chr-occupation and —meta-analysis-bp-profession flags added. From the innovation generate, —dfam constantly mistakes out with the right content, instead of maybe segfaulting, whenever no good instances can be found.
28 Oct: —meta-analysis-se-career flag additional, getting interoperation with recent PLINK dos.0 logistic regression yields (hence uses a beneficial ‘LOG(OR)_SE’ job term in order to disambiguate the standard error’s units).
Fixed «—design gen» permutation investigations insect
24 October: Fixed uninitialized-varying bug from inside the —dose + —q-score-variety. «—indep-pairwise 500kb . » functions safely again (the previous make requisite a gap till the ‘kb’).
4 Mar: Brackets during the demand-line assist text are actually included in a manner so much more similar to many other products. —testing today performs properly whenever a great numeric argument are step one early in the day the end.
twenty-six Will get (beta six): —merge-equal-pos bugfixes. If you put —merge-equal-pos with .bed+.bim+.fam filesets where allele acquisition have differed ranging from .bim documents, or that have people .ped+.chart fileset after all, i encourage redoing that are running.
: —meta-study ‘report-all’ today account amazing stats as opposed to ‘NA’ whenever N=1. Fixed a keen inaccuracy within the —adjust’s management of tiny p-opinions. —make-just-fam functions properly in just .fam input once more.
fourteen The fall of (beta 5): —document + —merge[-list] bugfix. map document try unsorted, but if you feel the chance i encourage redoing one —file + —mix and —file + —merge-record multiple-.ped merges did that have prior to plink step one.9 yields. (.sleep consolidating try unchanged, and you may —merge-number in place of —file try around never impacted.)
15 October: A2 allele has started to become consistently site towards chr3 within our 1000 Genomes phase 1 packages. As a general rule, do not expect you’ll remain REF/ALT alleles upright which have PLINK step 1.x, however, i made an effort to generate A2 consistently source in these data files nonetheless don’t quite ensure it is; disappointed about this. (As to the reasons was that it discovered today, over 2.five years following the fact? Due to the fact PLINK 2.0 now has an excellent —ref-from-fa flag that can easily seek out such error.)
thirteen Oct: «—freq counts» not any longer provides corrected abilities whenever alleles have been turned out of the first .bim/.bed acquisition. Repaired —logistic bug which could lead to spurious NA overall performance.
seven Oct: Fixed area-instance (two of the five haplotypes don’t have any understood observations) insect inside the —ld/—r2/—blocks/—clump’s mathematical phasing procedure. 32-part generate can now sort >2GB .sleep data instead of crashing. —annotate and you can —gene-report today work with —allow-extra-chr.
15 Aug: —lasso is today work properly when there will be samples along with covariates present but the head phenotype destroyed.
21 May: «—linear interaction intercourse» and you will «—logistic communications intercourse» today work effectively whenever no covariates are present. —tucc added to creativity generate.
20 February (beta 4): —pca var-wts today profile allele codes. Minor analytical phasing bugfix. —[max-]mac, —Roentgen, and you can —thin-indiv[-count] no more classified due to the fact unstable. PLINK dos.0 alpha builds are in reality offered.
So it insect try more inclined so you can result in in case your very first
13 November: —geno/—forgotten now reduce heterozygous haploid phone calls as nonmissing; it is in line with —mind, and you may PLINK step one.07’s behavior with —recode/—make-sleep effective. They might be today inconsistent as to what PLINK step one.07 performed instead —recode/—make-bed; play with —make-sleep + —set-hh-lost earliest if you’d like the outdated behavior. «—ci 0.95» no more produces ‘L94’/’U94’ line labels whenever plink will get unfortunate which have rounding. Small —exclude/—extract/—flip bugfix to own input files no newline at the bottom. —qfam[-within] bugfix. —amount ‘sex’ modifier now functions securely whenever some products was basically blocked away (age.grams. as certain phenotypes was in fact missing).
20 Sep: VCF export no more removes an enthusiastic alt allele missing regarding quick dataset, on account of a beneficial retroactive modify towards the VCF specs.