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Lactoferrin-containing immunocomplexes generate the conversion of human macrophages from M2- into M1-like phenotype. Endothelial TLR4 and the microbiome push cerebral cavernous malformations. 60. Jiang R, Lopez V, Kelleher SL, Lönnerdal B. Apo- and holo-lactoferrin are both internalized by lactoferrin receptor by means of clathrin-mediated endocytosis but differentially influence ERK-signaling and cell proliferation in Caco-2 cells.…

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